Jennifer Fish.

Jennifer L. Fish

Associate Professor, Graduate Coordinator

Pronouns
She/Her/Hers
College
College of Sciences
Department
Biological Science
Phone
978-934-6675
Office
Olsen Hall, Room 204
Email
Jennifer_Fish@uml.edu
Links

Expertise

Evolutionary and Developmental Biology, Craniofacial Development, Fgf8 signaling in Development, SATB2-Associated Syndrome

Research Interests

Developmental mechanisms generating variation in development, evolution, and disease; Regulation of gene dosage during development; Evolution of vertebrate morphology

Education

Ph.D., Max Planck Institute of Cell Biology and Genetics, 2003-2007 
M.A., Biological Anthropology, Arizona State University, 1998-2000 
B.S. Molecular and Cellular Biology (with Honors), University of Arizona, 1990-1994 

Selected Awards and Honors

2025 Marylou Buyse Distinguished Scientist Award from the Society of Craniofacial Genetics and Developmental Biology
2020 Award for Excellence in Graduate Teaching, University of Massachusetts Lowell
2017 Teaching Excellence Award, Department of Biological Sciences
2009 Winner, Roberts Open Competition, King’s College London (£1500 for the London Area Development and Evolution Network seminar series)
2011-2014 NIH (NIDCR) F-32 Post-Doctoral Fellowship (5F32DE021929)
2007-2010 Human Frontiers Long Term Fellowship (LT01061/2007-L)
2007 EMBO Post-doctoral Fellowship, (declined)

Selected Publications

  • Collu R, Zarate YA, Xia W, Fish JL*. Individuals with SATB2-associated syndrome have impaired vitamin and energy metabolism pathways. Metab Brain Dis. 2024 Nov 14;40(1):3. doi: 10.1007/s11011-024-01465-x. PubMed PMID: 39541055.
  • Etiology of craniofacial and cardiac malformations in a mouse model of SF3B4-related syndromes. Kumar S, Bareke E, Lee J, Carlson E, Merkuri F, Schwager EE, Maglio S, Fish JL, Majewski J, Jerome-Majewska LA. Proc Natl Acad Sci U S A . 2024 Sep 24;121(39):e2405523121.
  • Splicing is dynamically regulated during limb development. Driscoll S, Merkuri F, Chain FJJ, Fish JL*. Sci Rep. 2024 Aug 27;14(1):19944. doi: 10.1038/s41598-024-68608-z.
  • Fibroblast growth factors- An introduction to our primer series. Fish JL*. Differentiation. 2024 Sep-Oct;139:100804. doi: 10.1016/j.diff.2024.100804. Epub 2024 Aug 2.
  • Abnormalities in pharyngeal arch-derived structures in SATB2-associated syndrome. Zarate YA, Bosanko K, Derar N, Fish JL*. Clin Genet. 2024 Aug;106(2):209-213. doi: 10.1111/cge.14540. Epub 2024 May 1.
  • Bone health in SATB2-associated syndrome: Results from a large prospective cohort and recommendations for surveillance. Zarate YA, Bosanko K, Andres A, Fish JL. Am J Med Genet A. 2024 Feb;194(2):203-210. doi: 10.1002/ajmg.a.63421. Epub 2023 Oct 2.
  • Zbasnik N, Fish JL*. Fgf8 regulates first pharyngeal arch segmentation through pouch-cleft interactions. Front Cell Dev Bio 2023 May (11) doi:10.3389.fcell.2023.
  • Zbasnik N, Dolan K, Buczkowski SA, Green RM, Hallgrímsson B, Marcucio RS, Moon AM, Fish JL*. Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships. Dev Dyn. 2022 Oct;251(10):1711-1727. doi: 10.1002/dvdy.501. Epub 2022 Jun 9. PubMed PMID: 35618654; PubMed Central PMCID: PMC9529861.

Selected Contracts, Fellowships, Grants and Sponsored Research

R15 DE033850 (Principal Investigator: J. Fish) 7/01/2024 – 6/30/2027
NIH/NIDCR “Molecular and cellular mechanisms underlying Fgf8-dosage mediated defects in jaw size and symmetry”
Role: Principal Investigator

R03 DE028984 (Principal Investigator: J. Fish) 8/01/2020 – 7/31/2022 NIH/NIDCR ““Cellular mechanisms underlying Fgf8-mediated asymmetry of the pharyngeal endoderm” Role: Principal Investigator

2R15 DE026611 (Principal Investigator: J. Fish) 7/01/2020 – 6/30/2023 NIH/NIDCR “Molecular mechanisms underlying variation in severity of craniofacial disease” Role: Principal Investigator

(Principal Investigator: J. Fish) 11/01/2019 – 10/31/2020 SATB2 Foundation “Determining SATB2-mediated expression in human hippocampal neurons.” Role: Principal Investigator

R15 DE026611 (Principal Investigator: J. Fish) 12/15/2016 – 12/14/2019 NIH/NIDCR “Molecular mechanisms underlying variation in severity of craniofacial disease” Role: Principal Investigator

R01 DE016402 (Principal Investigator: R. Schneider) 7/01/2015 – 6/30/2018 NIH/NIDCR “Mesenchymal Regulation of Osteogenesis” Role: Co-Investigator, sub-contract to UML

R01 DE019638 (Principal Investigators: R.Marcucio/B.Hallgrimsson) 1/01/2016 – 12/31/2017 NIH/NIDCR “The Role of Continuous Phenotypic Variation in Structural Defects of the Face” Role: Co-Investigator, sub-contract to UML